Safest way to trade on binance?

Hello

Something not clear to me, is it possible to trade on binance while your coins stay in the trust wallet or ledger or do u just send them over for the trading session and then need to send them back after?

Like can i trade from my ledger while the funds stay on the ledger, or how does this interaction work. I know it goes through the bnb chain. But is everything running from the ledger or is it moved back and forth.

Just wondering how people trade with large amounts, do they just send them back after trading or keep them on exchange or swap them with trustwallet or ledger.

Thx in advance